Molecular research LP MR DNA http://www.mrdnalab.com introduced 16s , ITS and 18s long read diversity assays using Pac Bio when the sequel instrument was first launched.. They innovated the techniques to obtain good data at a reasonable price. For large projects price can be as low as $75/sample for over 5000 reads average. Of course, you can obtain as much data as you need for your samples this is just an example. Since the launch of the sequel II MR DNA has continued to advance the technology with greater quality and lower pricing. THey have a customizable platform now that can utilize any long amplicon no matter what the target for this technique.
Bacteria, archaea, eukaryotes, protozoa, fungi or any other target can now be evaluated with a much higher level of taxonomic classification. Unlike the short read technologies which can get us 2 or 3 variable regions we are able with the 16s to sequence with HI FI accuracy all 9 of the 16s variable regions.
our high definition taxonomic identifications for isolates follow along this same technology . no low quality sanger data .. This data tends to have extremely high quality scores, throughout the 16s, ITS1-4, 18s genes so that the ability of classification to go down even to the species level is possible with a diversity assay. Prices have come down so far and we are able to work with almost any type of DNA sample.
We have a full bioinformatics service potential with these long reads. contact MR DNA by going to their website http://www.mrdnalab.com .. at the top of every page is their email address info@mrdnalab.com.. so easy tell them what you want to send (how many samples) .. what you want to evaluate and they will take great care of you . Instantly go from a customer to a part of the MR DNA family .
Here’s a comprehensive content draft tailored for a webpage focused on long-read high-fidelity diversity sequencing:
Long-read high-fidelity sequencing represents a cutting-edge advancement in genomics, unlocking unparalleled insights into the complexity of microbial, fungal, and other biological communities. This powerful sequencing technology excels in generating long, contiguous reads with exceptional accuracy, making it ideal for exploring genetic diversity across metagenomes, microbiomes, and even complex eukaryotic genomes. By combining length and precision, high-fidelity sequencing provides a more comprehensive understanding of genetic variability and structural variations that were previously difficult to detect.
This technology is particularly transformative for microbiome studies, where capturing the full genetic repertoire of bacteria, fungi, archaea, and viruses is critical. Long-read sequencing accurately resolves species-level differences and uncovers functional genes, enabling researchers to better understand metabolic pathways, symbiotic relationships, and environmental interactions. For example, it enables the differentiation of closely related species, resolves complex repeat regions, and identifies novel genes in functional assays, all of which are pivotal for advancing fields like human health, agriculture, and environmental science.
High-fidelity sequencing offers immense advantages for diverse applications such as amplicon sequencing, metagenomics, and transcriptomics. It has been widely adopted for studying microbial ecology, tracking antibiotic resistance genes, and exploring the roles of unculturable microbes in dynamic ecosystems. This approach is also indispensable for structural variant analysis, isoform detection, and resolving telomere-to-telomere assemblies. The ability to generate long, accurate reads allows researchers to piece together highly repetitive or complex regions, leading to a deeper and more reliable understanding of genomes. With its broad applicability and unmatched performance, long-read high-fidelity sequencing is redefining the boundaries of genomic exploration.
At MR DNA, we harness the power of long-read high-fidelity sequencing to deliver robust, accurate, and comprehensive genomic solutions for a wide range of research needs. From environmental microbiomes to clinical diagnostics, our state-of-the-art facilities are equipped to tackle the most challenging sequencing projects with precision. Explore the future of genomics with MR DNA, where innovation meets excellence. Visit MR DNA to learn more.